Key West is known for fresh seafood, Caribbean flavors, and a lively dining scene, but it is also home to several excellent Mexican restaurants. Whether you’re craving tacos, enchiladas, fresh guacamole, or authentic Cuban-Mexican fusion, you’ll find plenty of great options across the island. Many restaurants also offer outdoor seating, live music, and colorful atmospheres that capture the spirit of Key West.
As you explore the area’s many Key West restaurants, consider adding these local favorites to your itinerary for a memorable meal.
Old Town Mexican Cafe
Old Town Mexican Cafe has been a favorite dining destination for decades. Located just off Duval Street, this family-owned restaurant serves classic Mexican dishes made with fresh ingredients and traditional recipes. Fresh salsa and house-made guacamole complement nearly every meal, while vegetarian and seafood options provide something for every guest. The casual atmosphere makes it an excellent stop after exploring historic Old Town or nearby attractions.
Dining here is one of the many enjoyable experiences that pair well with staying in our Key West vacation rentals close to downtown.
Amigos Tortilla Bar
Amigos Tortilla Bar offers a modern take on Mexican street food with a relaxed island atmosphere. Located near Mallory Square, it’s an easy place to grab lunch, dinner, or a late-night bite. The menu focuses on customizable tacos, burritos, bowls, and quesadillas filled with fresh proteins and vegetables. Popular choices include grilled mahi, steak, chicken, and pork, along with homemade salsas and flavorful toppings.
One of the restaurant’s highlights is its outdoor patio, where guests can enjoy tropical weather while dining. The casual setting and quick service make it ideal for families, couples, and groups exploring the waterfront.

Lolita’s Coastal Cocina
Lolita’s Coastal Cocina brings together Mexican flavors and fresh coastal ingredients in a bright, welcoming setting. The menu features tacos, ceviche, burritos, and seafood specialties made with locally inspired flavors. Guests can also enjoy handcrafted cocktails and a relaxed atmosphere that’s perfect for lunch, dinner, or happy hour. Its creative menu and convenient location make Lolita’s Coastal Cocina a great addition to any Key West dining itinerary.
Chico’s Cantina
Chico’s Cantina has built a loyal following by serving authentic Mexican cuisine in a welcoming environment. Although it’s a little away from the busiest tourist areas, many locals consider it one of the island’s hidden gems.
Favorites on the menu include:
- Carne asada
- Carnitas tacos
- Chile rellenos
- Fresh ceviche
- Homemade margaritas
Guests appreciate the generous portions, affordable prices, and attentive service. The restaurant also offers daily specials that feature seasonal ingredients and fresh seafood.
Whether you’re visiting for lunch or dinner, Chico’s Cantina provides an excellent alternative for travelers looking beyond the busiest dining districts. It’s another great reason why staying in our centrally located Key West rentals makes exploring every corner of the island easy.
Plan Your Visit
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Final Thoughts
From longtime local favorites to casual taco bars, Key West offers plenty of excellent places to enjoy Mexican cuisine. Each restaurant brings its own personality, menu specialties, and welcoming atmosphere, making it easy to find something that fits your taste.
Whether you’re enjoying classic enchiladas at Old Town Mexican Cafe, grabbing fresh tacos at Amigos Tortilla Bar, listening to live music at El Meson De Pepe’s, or discovering the authentic flavors at Chico’s Cantina, you’ll leave with another memorable dining experience during your island getaway.
Book Your Key West Vacation Rental with Historic Hideaways
After enjoying the best Mexican restaurants in Key West, relax in a home that puts you close to everything the island has to offer. At Historic Hideaways, we offer a carefully selected collection of vacation homes that combine comfort, charm, and convenient locations near beaches, attractions, shopping, and dining.
